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This article was developed and published in September 2018. Some of the views and evidence presented in this article may have evolved since their original development due to advancing literature and knowledge. Please look out for more recent articles, publications,...

This article was developed and published in September 2018. Some of the views and evidence presented in this article may have evolved since their original development due to advancing literature and knowledge. Please look out for more recent articles,...

  This article was developed and published in September 2018. Some of the views and evidence presented in this article may have evolved since their original development due to advancing literature and knowledge. Please look out for more recent articles,...

Extreme environments have been explored for over a century to understand human adaptation, extrapolate insights into comparative pathology, and extend human exploration These include spaceflight/microgravity, high altitude/hypobaric, undersea/hyperbaric,...

Over a century ago, carbohydrate restriction was a (and in many cases, the) means of extending the life of a newly diagnosed patient with Type-1 Diabetes. Then, there was only days, weeks, or months (sometimes years) to live (read more here). The scientific and...

Recently, our lab at the University of South Florida published the impact of ketone bodies on atrophy-based diseases with additional insights on exogenous ketones and ketone-based metabolism/signaling. This work encompasses >5-years worth of data, multi-institute...